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Glucosamine hydrochloride is an active pharmaceutical ingredient (API) that is used in the compounding of pharmaceutical drugs. It is a naturally occurring compound that is found in the human body, particularly in the fluid surrounding the joints. Glucosamine hydrochloride can be extracted from shellfish or produced by synthesizing glucose and ammonia.
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In compounding, glucosamine hydrochloride is most commonly used in the formulation of dietary supplements and over-the-counter pain medications. It is believed to have anti-inflammatory and joint-strengthening properties that make it an effective treatment for conditions such as osteoarthritis.
Due to its ability to stimulate the production of cartilage and synovial fluid, glucosamine hydrochloride is often used in combination with other ingredients (such as chondroitin sulfate) to help relieve joint pain and promote joint health. It is also commonly used as an alternative to non-steroidal anti-inflammatory drugs (NSAIDs) for patients who may be sensitive to those medications.
The United States Pharmacopeia (USP) sets standards for the quality, purity, and strength of glucosamine hydrochloride that is used in prescription or non-prescription drugs. This ensures that the compounded medications containing this API are safe and effective for patient use.